What is magnesium Oxide?

Magne­si­um oxide is a che­mi­cal com­pound with the formula MgO. Magne­si­um oxide is inor­ga­nic, con­sists of white crys­tals, and is nor­mal­ly inso­lu­b­le in water. It has a high ele­men­tal magne­si­um content of appro­xi­m­ate­ly 58–60 % and can be used in food sup­ple­ments where space is limited, such as tablets or cap­su­les. It is also often used to increase the magne­si­um content in pro­ducts that cannot be achie­ved with purely organic magne­si­um sources alone.

Overview:

  • Magne­si­um oxide, con­sists of a magne­si­um cation (Mg²⁺) and an oxygen anion (O²-)
  • Mole­cu­lar weight: 40.3 g/mol
  • Bulk Density: 150–850 g/L (depen­ding on product)
  • Formed by cal­ci­na­ti­on of magne­si­um hydr­o­xi­de or magne­si­um carbonate
  • Mineral content in %: Approx. 60 %

How is magnesium oxide produced?

Magne­si­um oxide is formed by cal­ci­na­ti­on (heating a che­mi­cal com­pound below its melting point to cause partial che­mi­cal decom­po­si­ti­on) of magne­si­um hydr­o­xi­de (Mg(OH)2) or magne­si­um car­bo­na­te (MgCO3). The cal­ci­na­ti­on tem­pe­ra­tu­re has a signi­fi­cant influence on the pro­per­ties of magne­si­um oxide (MgO).

In which industries and for which products can magnesium oxide be used?

In medi­ci­ne, it is used as an antacid and source of magne­si­um. In the food indus­try, it is regis­tered as a food addi­ti­ve E530, serves as a pH regu­la­tor and is also appro­ved for the for­ti­fi­ca­ti­on of food pro­ducts and sup­ple­ments with magnesium.

1. Crystal struc­tu­re and phase purity:

  • Low tem­pe­ra­tures: At low cal­ci­na­ti­on tem­pe­ra­tures, an amor­phous magne­si­um oxide is often obtained
  • Medium tem­pe­ra­tures: At these tem­pe­ra­tures, well-crystal­li­zed MgO is usually pro­du­ced. The struc­tu­re becomes denser and more crystal­li­ne, which can improve the mecha­ni­cal properties
  • High tem­pe­ra­tures: Very high cal­ci­na­ti­on tem­pe­ra­tures lead to a further increase in crystal­li­ni­ty. The resul­ting MgO is very stable and dense

2. Particle size and surface structure:

  • Low tem­pe­ra­tures: The resul­ting MgO often has a high spe­ci­fic surface area. This leads to a higher reac­ti­vi­ty, as more surface area is available for che­mi­cal reactions.
  • High tem­pe­ra­tures: The spe­ci­fic surface area decrea­ses. This can reduce the reac­ti­vi­ty of the MgO.

3. Porosity:

  • Low to medium tem­pe­ra­tures: MgO cal­ci­ned at lower tem­pe­ra­tures tends to have a higher poro­si­ty, which makes it sui­ta­ble for use as a cata­lyst or adsorbent.
  • High tem­pe­ra­tures: Poro­si­ty decrea­ses as the par­tic­les become denser and the pore struc­tu­re par­ti­al­ly closes. This can increase the density but reduce the spe­ci­fic surface area and porosity.

4. Reactivity and solubility:

  • Low tem­pe­ra­tures: Due to the higher spe­ci­fic surface area, the MgO is more reac­ti­ve and easier to dissolve.
  • High tem­pe­ra­tures: MgO cal­ci­ned at higher tem­pe­ra­tures has a lower reac­ti­vi­ty and solubility.

In which food supplements is magnesium oxide typically used?

Our Innova market rese­arch has shown that magne­si­um oxide is mainly pro­ces­sed in tablets and cap­su­les (see chart below). This is because magne­si­um oxide is ideal for this dosage form, as its high ele­men­tal magne­si­um content requi­res only a small of the raw mate­ri­al com­pared to other forms of magne­si­um com­pounds. By using our highly soluble magne­si­um oxide, effer­ve­s­cent tablets and powder can be added to the range of useful dosage forms.

Why is the solubility of magnesium important for liquid applications?

Espe­ci­al­ly in liquid appli­ca­ti­ons or dis­so­lu­ti­on appli­ca­ti­ons, the con­su­mer expects a residue and sedi­ment-free solu­ti­on. Product deve­lo­pers the­r­e­fo­re often look for mineral com­pounds that meet these requi­re­ments. In the past, the poor solu­bi­li­ty of magne­si­um oxide in water posed pro­blems for the food and sup­ple­ment indus­try. We have now found a solu­ti­on to this problem with our highly active and soluble magne­si­um oxide.

What makes our magnesium oxide a highly soluble magnesium oxide?

In tests with magne­si­um oxides in effer­ve­s­cent powders, we found that a highly active magne­si­um oxide variant dis­sol­ves sedi­ment- and residue-free during the dis­so­lu­ti­on time of the effer­ve­s­cent powder. The reason for this is the citric acid added to the solu­ti­on. It causes the solu­ti­on to acquire an acidic pH value and impro­ves the ioniza­ti­on (dis­so­lu­ti­on) of the magne­si­um oxide. This solu­bi­li­ty descri­bed in this expe­ri­ment is also trans­fera­ble to the much stron­ger stomach acid. The highly soluble magne­si­um oxide can be dis­sol­ved (ionized) by gastric acid, too, and thus, is bio­available. The descri­bed highly soluble magne­si­um oxide can the­r­e­fo­re be used in both dry and liquid appli­ca­ti­ons. Due to the high ele­men­tal magne­si­um content, only small quan­ti­ties of our highly active soluble magne­si­um oxide need to be applied to achieve the desired magne­si­um content in the end application.

Hochauflösendes Magnesiumoxid im Vergleich zu einem normalen Magnesiumoxid in Bezug auf Löslichkeit
The solu­bi­li­ty of the highly soluble magne­si­um oxide (right) com­pared to a regular magne­si­um oxide (left) in 2% citric acid without further addi­ti­ves is clearly recognizable.

Bioavailability of magnesium oxide

In general, regular magne­si­um oxides have very limited bio­avai­la­bi­li­ty due to their poor solu­bi­li­ty. By impro­ving the solu­bi­li­ty, the bio­avai­la­bi­li­ty is also increased – as seen in the example of our highly soluble magne­si­um oxide above. The bio­avai­la­bi­li­ty of magne­si­um oxide can also be influen­ced by the dosage form. A study shows that the bio­avai­la­bi­li­ty of magne­si­um oxide in effer­ve­s­cent tablets is twice as high com­pared to magne­si­um oxide in cap­su­les. This sug­gests that the dis­so­lu­ti­on of magne­si­um oxide in water (ioniza­ti­on to Mg2+) is an important pre­re­qui­si­te for its absorp­ti­on. Con­se­quent­ly, the bio­avai­la­bi­li­ty of dissolved/ionized magne­si­um oxide is com­pa­ra­ble to that of organic magne­si­um salts (e.g. magne­si­um citrate, magne­si­um glu­co­na­te, etc.). These fin­dings apply to the highly active magne­si­um oxide from MAGNESIA. This product offers good solu­bi­li­ty in diluted organic acids such as citric acid or malic acid, which are mainly used as aci­di­fiers in food sup­ple­ments. This makes our highly soluble magne­si­um oxide ideal for effer­ve­s­cent powders and tablets, which always contain an acid com­po­nent per se.

Highly soluble magnesium oxide – minimum order quantity and samples

Our highly soluble magne­si­um oxide is available in powder form. Unit sizes start from 25 kg. Samples are of course available to you free of charge. We also offer various other qua­li­ties of classic magne­si­um oxides for use in food and nut­ri­tio­nal sup­ple­ments. Feel free to contact us — our sales team and our nut­ri­tio­nists will be happy to support you.

MAGNESIA 2225020

Highly active soluble magne­si­um oxide, EP, USP, FCC
Ca. 57 % Mg

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Whitepaper

Read our white­pa­per on highly active and soluble magne­si­um oxide 

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