Highly soluble magnesium oxide

Phar­ma­ceu­ti­cal com­pa­nies are con­tin­u­ous­ly invest­ing in the devel­op­ment of user-friend­ly oral dosage forms to increase patient accep­tance and sim­pli­fy intake. These include effer­ves­cent tablets, chew­able tablets and dis­solv­ing pow­ders. These inno­v­a­tive for­mats allow for more flex­i­ble dos­ing and improve the treat­ment expe­ri­ence for patients, espe­cial­ly those with swal­low­ing dif­fi­cul­ties or an aver­sion to tra­di­tion­al tablets.

Innovation in the pharmaceutical industry: highly soluble magnesium oxide

In addi­tion to inno­v­a­tive dosage forms, well-known sub­stances are also gain­ing in impor­tance thanks to opti­mized man­u­fac­tur­ing process­es. For exam­ple, the phys­i­cal prop­er­ties of mag­ne­sium oxide (MgO), such as its sol­u­bil­i­ty, can be improved through sys­tem­at­ic mod­i­fi­ca­tions, open­ing up new areas of appli­ca­tion. Such mod­i­fi­ca­tions make it pos­si­ble to increase the effec­tive­ness of exist­ing prepa­ra­tions and min­i­mize side effects. One of these inno­va­tions is MAG­NE­SI­A’s high­ly sol­u­ble mag­ne­sium oxide, which is specif­i­cal­ly qual­i­fied for use in the phar­ma­ceu­ti­cal indus­try and whose prop­er­ties we present to you below.

What is highly soluble magnesium oxide?

Mag­ne­sium oxide is an inor­gan­ic com­pound of mag­ne­sium and oxy­gen. An opti­mized grade is char­ac­ter­ized by improved sol­u­bil­i­ty in organ­ic acids or gas­tric acid, which allows the mag­ne­sium con­tent in phar­ma­ceu­ti­cal prod­ucts to be increased effi­cient­ly. High­ly sol­u­ble mag­ne­sium oxide is obtained by spe­cial man­u­fac­tur­ing process­es, includ­ing the cal­ci­na­tion of mag­ne­sium hydrox­ide or mag­ne­sium car­bon­ate at con­trolled tem­per­a­tures. These process­es opti­mize the sol­u­bil­i­ty and thus the bioavail­abil­i­ty of mag­ne­sium, mak­ing it a valu­able ingre­di­ent for phar­ma­ceu­ti­cal applications.

What are the benefits of highly soluble magnesium oxide?

A key advan­tage of this high­ly sol­u­ble form is its increased bioavail­abil­i­ty. As the mag­ne­sium is more eas­i­ly absorbed, the active ingre­di­ent can devel­op its ther­a­peu­tic effect more effec­tive­ly and even com­pete with known organ­ic mag­ne­sium com­pounds. This improved absorp­tion means that patients need to take low­er dos­es to achieve the same effect, which reduces the risk of unwant­ed side effects.

How can highly soluble magnesium oxide be used in the pharmaceutical industry?

High­ly sol­u­ble mag­ne­sium oxide is par­tic­u­lar­ly suit­able for inno­v­a­tive dosage forms such as effer­ves­cent tablets and effer­ves­cent pow­ders. The high mag­ne­sium den­si­ty allows the vol­ume of prepa­ra­tions to be reduced, result­ing in more com­pact and attrac­tive prod­ucts for con­sumers. These prop­er­ties make it ide­al for a wide range of appli­ca­tions, includ­ing sports nutri­tion, dietary sup­ple­ments as well as OTC and pre­scrip­tion drugs.

In addi­tion to its role as an active ingre­di­ent, mag­ne­sium oxide also offers func­tion­al ben­e­fits. Thanks to its clear­ly alka­line pH val­ue, it can improve the micro­bi­o­log­i­cal safe­ty of phar­ma­ceu­ti­cal appli­ca­tions. This antimi­cro­bial prop­er­ty con­tributes to extend­ed shelf life and increased prod­uct safe­ty. In addi­tion, mag­ne­sium oxide helps to sta­bi­lize cer­tain chem­i­cal reac­tions in phar­ma­ceu­ti­cal prod­ucts, ensur­ing qual­i­ty over the entire shelf life. An exam­ple of this is the use of mag­ne­sium oxide in tablet for­mu­la­tions to sta­bi­lize acid-sen­si­tive active ingre­di­ents that could oth­er­wise lose effi­ca­cy dur­ing storage.

The ver­sa­til­i­ty of mag­ne­sium oxide is demon­strat­ed by its numer­ous appli­ca­tions: It is used in antacids to neu­tral­ize excess stom­ach acid and in food sup­ple­ments for the tar­get­ed sup­ply of mag­ne­sium. It is also used in spe­cial prepa­ra­tions for mus­cle regen­er­a­tion after phys­i­cal exer­tion. This wide range of appli­ca­tions makes high­ly sol­u­ble mag­ne­sium oxide an essen­tial raw mate­r­i­al in the mod­ern phar­ma­ceu­ti­cal industry.